Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | BIOCARTA_MAPKINASE SIGNALING PATHWAY |
| Enrichment Score (ES) | -0.5628416 |
| Normalized Enrichment Score (NES) | -1.6289984 |
| Nominal p-value | 0.009208103 |
| FDR q-value | 0.20533201 |
| FWER p-Value | 0.982 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAP3K12 | 1417115_at 1438908_at 1456565_s_at | 349 | 1.911 | 0.0326 | No | ||
| 2 | MYC | 1424942_a_at | 351 | 1.908 | 0.0811 | No | ||
| 3 | MAPK13 | 1448871_at | 1070 | 1.134 | 0.0771 | No | ||
| 4 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 1312 | 0.982 | 0.0910 | No | ||
| 5 | MAPK10 | 1437195_x_at 1448342_at 1458002_at 1458062_at 1458513_at | 1313 | 0.982 | 0.1160 | No | ||
| 6 | MAX | 1423501_at | 1519 | 0.887 | 0.1292 | No | ||
| 7 | MAP3K7 | 1419988_at 1425795_a_at 1426627_at 1449693_at 1455441_at 1458787_at | 1785 | 0.784 | 0.1370 | No | ||
| 8 | CEBPA | 1418982_at | 4249 | 0.342 | 0.0331 | No | ||
| 9 | RAC1 | 1423734_at 1437674_at 1451086_s_at | 4418 | 0.331 | 0.0339 | No | ||
| 10 | RPS6KA1 | 1416896_at | 4668 | 0.312 | 0.0304 | No | ||
| 11 | MEF2D | 1421388_at 1434487_at 1436642_x_at 1437300_at 1458901_at | 6003 | 0.229 | -0.0247 | No | ||
| 12 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 6350 | 0.212 | -0.0352 | No | ||
| 13 | MAP2K1 | 1416351_at | 6588 | 0.201 | -0.0409 | No | ||
| 14 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 7004 | 0.182 | -0.0552 | No | ||
| 15 | PAK2 | 1434250_at 1454887_at | 8173 | 0.134 | -0.1052 | No | ||
| 16 | MAP3K13 | 1430137_at 1440749_at 1447699_at | 8200 | 0.133 | -0.1030 | No | ||
| 17 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 8428 | 0.124 | -0.1102 | No | ||
| 18 | MAPK12 | 1447823_x_at 1449283_a_at | 8469 | 0.123 | -0.1089 | No | ||
| 19 | MAP4K5 | 1427083_a_at 1427084_a_at 1427376_a_at 1440059_at 1445426_at 1446348_at 1447204_at | 9378 | 0.091 | -0.1481 | No | ||
| 20 | MAP4K3 | 1444406_at | 11282 | 0.028 | -0.2344 | No | ||
| 21 | MAP2K5 | 1417854_at 1430180_at 1453712_a_at 1455941_s_at | 11429 | 0.023 | -0.2405 | No | ||
| 22 | MAPK9 | 1421876_at 1421877_at 1421878_at | 12024 | 0.002 | -0.2675 | No | ||
| 23 | GCK | 1419146_a_at 1425303_at | 12044 | 0.002 | -0.2684 | No | ||
| 24 | MAPK11 | 1421925_at 1421926_at | 12072 | 0.001 | -0.2696 | No | ||
| 25 | HRAS | 1422407_s_at 1424132_at | 12396 | -0.011 | -0.2840 | No | ||
| 26 | ATF2 | 1426582_at 1426583_at 1427559_a_at 1437777_at 1452116_s_at 1459237_at | 13145 | -0.039 | -0.3172 | No | ||
| 27 | MAP2K3 | 1425456_a_at 1451714_a_at | 14805 | -0.108 | -0.3903 | No | ||
| 28 | MAP3K8 | 1419208_at | 14885 | -0.112 | -0.3911 | No | ||
| 29 | PAK1 | 1420979_at 1420980_at 1450070_s_at 1459029_at | 15454 | -0.139 | -0.4135 | No | ||
| 30 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 16000 | -0.170 | -0.4341 | No | ||
| 31 | FOS | 1423100_at | 16233 | -0.185 | -0.4400 | No | ||
| 32 | MAP3K2 | 1422250_at | 16396 | -0.195 | -0.4425 | No | ||
| 33 | JUN | 1417409_at 1448694_at | 17249 | -0.260 | -0.4748 | No | ||
| 34 | MEF2C | 1421027_a_at 1421028_a_at 1424852_at 1439946_at 1445420_at 1446484_at 1451506_at 1451507_at 1458551_at | 17535 | -0.286 | -0.4805 | No | ||
| 35 | MAPK7 | 1418060_a_at | 18389 | -0.394 | -0.5095 | No | ||
| 36 | MAP3K4 | 1421450_a_at 1447667_x_at 1450253_a_at 1459800_s_at | 19557 | -0.628 | -0.5469 | Yes | ||
| 37 | MAP3K11 | 1450669_at | 19668 | -0.656 | -0.5352 | Yes | ||
| 38 | MAPK3 | 1427060_at | 19743 | -0.679 | -0.5214 | Yes | ||
| 39 | MAP3K3 | 1426686_s_at 1426687_at 1436522_at | 19854 | -0.713 | -0.5083 | Yes | ||
| 40 | MAP3K14 | 1422999_at 1434364_at | 20042 | -0.774 | -0.4971 | Yes | ||
| 41 | MAP4K4 | 1422615_at 1440609_at 1448050_s_at 1459912_at | 20107 | -0.798 | -0.4798 | Yes | ||
| 42 | CREB1 | 1421582_a_at 1421583_at 1423402_at 1428755_at 1452529_a_at 1452901_at | 20213 | -0.844 | -0.4631 | Yes | ||
| 43 | RAF1 | 1416078_s_at 1425419_a_at | 20370 | -0.914 | -0.4471 | Yes | ||
| 44 | MAP3K1 | 1424850_at | 20926 | -1.284 | -0.4398 | Yes | ||
| 45 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 21011 | -1.366 | -0.4089 | Yes | ||
| 46 | MAP2K6 | 1426850_a_at 1459292_at | 21374 | -1.800 | -0.3797 | Yes | ||
| 47 | ELK1 | 1421896_at 1421897_at 1446390_at | 21389 | -1.836 | -0.3337 | Yes | ||
| 48 | MEF2A | 1421252_a_at 1425426_a_at 1427185_at 1427186_a_at 1452347_at | 21450 | -1.947 | -0.2869 | Yes | ||
| 49 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 21451 | -1.949 | -0.2374 | Yes | ||
| 50 | ARAF | 1426602_at 1428607_at 1435566_s_at 1440764_at 1445693_at | 21471 | -1.995 | -0.1875 | Yes | ||
| 51 | STAT1 | 1420915_at 1440481_at 1450033_a_at 1450034_at | 21604 | -2.287 | -0.1355 | Yes | ||
| 52 | SP1 | 1418180_at 1448994_at 1454852_at | 21713 | -2.651 | -0.0730 | Yes | ||
| 53 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 21823 | -3.268 | 0.0051 | Yes |
